Table III.
Characteristics of Drug Release from Alginate Matrix Tablets Prepared with Different Hardness and Drug Load
Formulation code | Hardness (kgf) | AUC (% mg h/ml) 0–12 h (mean ± SD, n = 4) | Formulation code | Drug load (mg) | AUC (% mg h/ml) 0–12 h (mean ± SD, n = 4) |
---|---|---|---|---|---|
F7 | 3.5 | 866.51 ± 0.34 | F11 | 60 | 962.23 ± 2.33 |
F8 | 4.5 | 856.62 ± 5.78 | F12 | 90 | 982.51 ± 0.93 |
F9 | 5.5 | 844.16 ± 3.28 | F13 | 120 | 987.61 ± 0.53 |
F10 | 6.5 | 797.25 ± 4.24 | |||
ANOVA test | p < 0.05 | ANOVA test | p < 0.05 |
AUC Area Under the Curve