Table I.

In Vitro Activity of both Formulations on Intramacrophagic Amastigotes of L. donovani

Formulation code	IC50 (µg/mL)
LBL-DOX	0.16 ± 0.05
Plain DOX	0.30 ± 0.04

The IC₅₀ (concentration of drug that inhibits 50% of L. donovani amastigotes) was obtained by plotting a graph of the percentage of inhibition at different concentrations of all the observations using Origin 6.1 version software and expressed in microgram per millimeter. The results are expressed as ±SD of three separate experiments

LBL-DOX doxorubicin-loaded [(SA/PRM)₅] multilayers