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Particle Size of Ofloxacin Multilamellar and Reverse-Phase Evaporation Liposomes
| Liposomal Lipid Composition | Molar Ratio | Liposomal Charge | Mean Diameter (nm) for REVs | Mean Diameter (nm) for MLVs |
|---|---|---|---|---|
| DPPC/CH | 4:3 | Neutral | 1,025 | 1,378 |
| DPPC/CH/ DP | 4:3:1 | Negative | 1,210 | 1,735 |
| DPPC/CH/SA | 4:3:1 | Positive | 1,460 | 1,912 |
CH cholesterol, DP dihexadecyl hydrogen phosphate, SA stearylamine, DPPC dipalmitoyl-l-α-phospatidylcholine, REVs reverse-phase evaporation vesicles, MLVs multilamellar vesicles
