. 2009 Nov 21;10(4):1381. doi: 10.1208/s12249-009-9341-z

Table III.

Point and Interval Hypothesis Tests: Applicability of the Present Method in Pharmaceutical Formulations and Its Comparison with the Reference Method at 95% Confidence Level

Pharmaceutical formulations	Proposed method		Reference method		t and F values^b	θ_L ^c	θ_U ^c
Capsule	Recovery (%)	RSD^a (%)	Recovery (%)	RSD^a (%)	t and F values^b	θ_L ^c	θ_U ^c
Spectra-25 (Rexcin Pharma)	99.99	0.232	100.17	0.338	t = 0.983	0.993	1.003
					F = 1.458
Doxetar-25 (Torrent Labs Pvt. Ltd)	99.99	0.236	100.17	0.338	t = 0.956	0.995	1.002
					F = 1.432

^aMean for five independent analyses

^bTheoretical t (ν = 8) and F values (ν = 4, 4) at 95% confidence level are 2.306 and 6.39, respectively

^cA bias, based on recovery experiments, of ±2% is acceptable