Table IV.

Comparison of the Developed Method with Other Existing Methods for the Determination of Doxepin Hydrochloride

Techniques/reagents	Linear range (μg ml−1)	Limit of detection (ng ml−1)	RSD (%)	References
Spectrofluorimetry
9,10-dimethoxyanthracene-2-sulfonate	0.25–3	220	2.1	(14)
Eosin Y	0.1–0.8	0.95	0.59	This work
Spectrophotometry
Ti(IV) thiocyanate	5–50	340	0.43	(12)
Fe(III) thiocyanate	3–30	260	0.32	(12)
3-methylbenzothiazolin-2-one	0.8–10	–	–	(10)
HPLC	30–70	–	<2	(6)
Capillary electrophoresis	0.005–0.8	1	4.2	(8)