Table 2.

Comparison of the surgical approaches adopted by the three largest published series of total pancreatectomy and islet autotransplantation

	Leicester series (55 to date)	Minnesota series (>200 to date)	Cincinnati series (>130 to date)
Pancreatic resection and duodenectomy	Total with partial duodenectomy Pylorus preserving and preserving 4th part of duodenum Pancreas resected as a whole	Earlier series were near total with preservation of entire duodenum Past 15 years, partial duodenectomy, preserving pylorus and 4th part of duodenum Pancreas resected as a whole	For near-total pancreatectomy, a small rim (<5%) of pancreas left along with the C-loop of the duodenum, with the common bile duct and pancreaticoduodenal artery and entire duodenum left intact For total pancreatectomy, partial duodenum with or without preserving the pylorus Pancreas divided at the level of superior mesenteric artery with the distal portion sent for islet isolation while dissection around the head of pancreas continues
Spleen	Spleen preserving, supplied by the short gastric vessels	Splenectomy performed unless it retains an absolutely normal appearance after hilar ligation	Routine splenectomy
Reconstruction	End-to-end duodeno-duodenostomy or end-to-side duodenojejunostomy Choledochoduodenostomy	End-to-end duodeno-duodenostomy or end-to-side duodenojejunostomy Choledochoduodenostomy	Not required in near-total pancreatectomy. Side-to-side gastrojejunostomy or end-to-side duodenojejunostomy End-to-side hepaticojejunostomy