Table 4.
Pain control following total pancreatectomy and islet autotransplantation
| Centres | Minneapolis | Leicester | Cincinnati | Alabama |
|---|---|---|---|---|
| Published series (where data was extracted from) | Gruessner et al. 200419aWahoff et al. 199510b | Garcea et al. 20099 | Ahmad et al. 200512Rodriguez Rilo et al. 200315c | Argo et al. 20083 |
| Opiate requirements | 40% resolved, 32% improved, 12% no change, 16% lost to follow-upa81% of narcotic dependent patients pre-op became independent post-opb | 91% patients requiring opiates pre-op → 40% post-op Only 16% requiring opiate after 60 months | Morphine equivalents: 206 mg (0–1120 mg) pre-op → 90 mg (0–520 mg) post-op (P = 0.005) | 14.3% no narcotic use; 50% decreased; 35.7% no change at 3-months follow up 60% reported no narcotic use; 20% decreased; 20% no change at 6-months follow up |
| Pain score | Pain score 9.6 +/− 0.9 → 3.8 +/− 1.5 (P < 0.05)b | Severity of pain: 10 → 3 (P < 0.05) Frequency of pain: 10 → 2 (P < 0.05) | Pain rating index 37 → 11c (P < 0.01) | Not reported |
a
Sample size = 112;
b
Sample size = 48;
c
Sample size = 22