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. 2009 Dec 10;119(1):7–35. doi: 10.1007/s00401-009-0619-8

Fig. 5.

Fig. 5

Reactive astrogliosis demarcates cerebral microinfarcts. Survey image of cerebral cortex of an elderly individual showing microinfarcts (arrows) highlighted by dense clusters of prominently reactive astrocytes that stain intensely for GFAP. Fibrous astrocytes within subcortical white matter (wm) exhibit GFAP staining, whereas GFAP is not detectable in most protoplasmic gray matter astrocytes remote from the lesions in this specimen. H haematoxylin counterstain. Scale bar 180 μm