TABLE 1.
Marker | day 0 | day 1 | week1 | week 2 | week 3 | week5 | ≥ 9 months |
---|---|---|---|---|---|---|---|
MITF1 | + | ++ | +++ | ++ | + | + | + |
TYR1 | + | + | ++ | +++ | ++ | ++ | + |
Pmel171 | + | + | ++ | +++ | ++ | ++ | + |
MART11 | + | + | ++ | +++ | ++ | ++ | + |
Melanin 2 | + | + | ++ | ++ | ++ | ++ | + |
Melanin 3 | + | + | + | + | ++ | ++ | + |
Melanosome redistribution | + | + | ++ | + | + | + | + |
Melanocyte density 4 | + | + | + | + | + | ++ | + |
Visible skin color5 | + | ++ | +++ | +++ | +++ | +++ | + |
assessed as intensity of staining.
Melanin content as assessed by immunohistochemistry of Fontana Masson stain.
Melanin content as assessed by chemical analysis.
comparable results were obtained with stains for TYR, MART1, Pmel 17 and MITF.
measured as reflectance.