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. Author manuscript; available in PMC: 2010 Dec 10.
Published in final edited form as: Neuron. 2009 Dec 10;64(5):692–706. doi: 10.1016/j.neuron.2009.10.004

Figure 9. Summary of the mechanism to determine oscillation frequency.

Figure 9

(A1) Long odor pulses cause ORNs to undergo sensory adaptation.

(A2) When odor exposure is lengthy, active ORNs adapt, decreasing their firing rates.

(A3) The lower ORN firing rates reduce excitatory drive to PNs.

(A4) As each PN receives less intense input, its firing rate decreases and oscillations slow.

(B1) When odor concentration is reduced, smaller populations of ORNs respond.

(B2) However, the responsive ORNs continue to fire at high rates.

(B3) Thus, the most active PNs continue to receive strong input from responsive ORNs…

(B4) and oscillation frequency remains stable across broad ranges of odor concentration.