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. Author manuscript; available in PMC: 2009 Dec 30.
Published in final edited form as: Hum Mol Genet. 2006 Sep 19;15(21):3132–3145. doi: 10.1093/hmg/ddl253

Figure 5.

Figure 5

COMTVal158Met polymorphism in schizophrenia and bipolar disorder. The COMT Val158Met polymorphism analysis was performed as described under Materials and Methods. Briefly, COMT gene-specific PCR products encompassing the polymorphic region were cleaved by the NlaIII restriction enzyme to an 88 bp fragment and two variable fragments 96 and 114 bp in length, which indicated the Met and Val alleles, respectively. The first lane contains a 50 bp DNA ladder used as the marker. Representative examples are shown for heterozygosity (lanes 2, 4, 5 and 7), Met homozygosity (lanes 3 and 9) and Val homozygosity (lanes 6, 8 and 10).