Table 4.

MB-COMT expression analysis of HTBRC samples by qRT-PCR

Samples	1	2	3	4	5	6	7	8	9	10
Brain laterality	R	R	L	L	L	L	R	L	R	L
Methylation status	M	M	M	M	U	U	U	U	U	M
Relative expression of MB-COMT	0.84	1.15	0.5	0.87	2.45	2.3	4.6	2.3	4.6	1.7
Relative fold change	Controls = 1.16 (SD = 0.76)					SCZ = 3.1 (SD = 1.4)
Patients versus controls	(t = −2.74, P = 0.026)

R, right; L, left; M, methylated; U, unmethylated.

Samples 1–5 are from controls and 6–10 from schizophrenic patients. CT value was used for relative quantitation of MB-COMT expression (normalized to GADPH gene expression as an internal control). Fold changes was calculated as 2^–△△CT.