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The mean (SD) annualized Brain Boundary Shift Integral (BBSI) value for uncorrected and phantom corrected images, registered using 6 or 9DOF, and for control and AD subjects.
| Correction | Control (n = 79) | AD (n = 50) |
|---|---|---|
| None | 0.51 (0.93) | 1.38 (0.98) |
| Phantom corrected | 0.51 (0.86) | 1.37 (0.91) |
| 9DOF registration | 0.49 (0.81) | 1.34 (0.89) |
The BBSI value gives a measure of overall brain atrophy. This is a volume change expressed as a percentage of baseline brain volume, per year.
