1. |
Protecting neurons and axons from secondary injury |
2. |
Elevating intrinsic capacity of injured CNS axons to regenerate |
3. |
Bridging the lesion gap with permissive cellular transplants and adhesion molecules |
4. |
Reducing glial scar formation and deposition of chondroitin sulfate proteoglycans |
5. |
Overcoming CNS myelin-associated inhibitors |
6. |
Enhancing directional growth with neurotrophic factors |
7. |
Enabling reinnervation of denervated targets |
8. |
Retraining the nervous system to use the therapeutic interventions |