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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2010 Jan;19(1):2–9. doi: 10.1002/pds.1845

Figure 1. Nonvertebral Fracture Rates Within 12 Months of Treatment Initiation by Disease Risk Score (DRS) Quintile and Drug Exposure.

Figure 1

Full cohort DRS: state-specific DRS equation created in the full cohort (covariates + exposures terms) and applied to all individuals based on individual covariate values (exposures excluded from equation)

Unexposed cohort DRS: state-specific DRS equations created among unexposed cohort (alendronate users) and then applied to all individuals based on individual covariate values

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