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. 2009 Oct 23;38(1):e4. doi: 10.1093/nar/gkp853

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© The Author(s) 2009. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Plots showing MMBGX log expression values of three types of genes at different brain/heart mixture levels. Fifty transcripts for which P(μ_g9−μ_g1 < 0) = 0, P(μ_g9−μ_g1 < 0) = 1 and 0.45 < P(μ_g9−μ_g1 < 0) < 0.55) were randomly chosen and defined as ‘brain-expressed’, ‘heart-expressed’ and ‘equally-expressed’. The group mean of the nine mixture levels was subtracted from the nine values for each group of fifty transcripts and plotted (A–C). As expected, the intensities of (A) brain-, (B) equally and (C) heart-expressed transcripts are upward-sloping, flat and downward-sloping respectively, showing that MMBGX is adequately capturing concentration changes.