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. 2009 Oct 21;38(1):117–130. doi: 10.1093/nar/gkp863

Figure 5.

Figure 5.

Increased frequency of HuD-binding motifs in mRNAs upregulated in the brains of HuD overexpressor mice. (A) Frequency of HuD-binding motif 1 in the 5′ UTR, CR and 3′ UTR of mouse genome (white bars), Affymetrix 430 2.0 chip genes (light grey bars), forebrain transcripts (dark grey bars) and mRNAs upregulated in HuD-Tg mice (black bars). (B) Same analysis for HuD-binding motif 2. (C) Frequency of motif 3 in the same gene datasets. ***P < 0.0001 HuD-Tg mice versus each of the three reference sets (genome, chip and forebrain), (a) P < 0.02 versus genome and chip, (b) P < 0.05 versus genome and chip and (c) P < 0.05 versus all three reference sets.