Table 2.
Person-Years of Follow-Up | No. of Deaths | Mortality Rate | Hazard Ratio | 95% Confidence Interval | P Value From Trend Test | |
Body mass indexc at age 50 yearsd | <0.01 | |||||
18.5–<25 | 919,713 | 7,302 | 792 | 1.00 | Referent | |
25–<30 | 690,634 | 6,110 | 932 | 1.08 | 1.05, 1.12 | |
30–<35 | 148,482 | 1,598 | 1,287 | 1.48 | 1.40, 1.57 | |
≥35 | 43,620 | 553 | 1,676 | 2.08 | 1.91, 2.27 | |
Waist circumference categoryde | <0.01 | |||||
1 | 767,082 | 5,845 | 812 | 1.00 | Referent | |
2 | 480,615 | 3,981 | 839 | 1.02 | 0.98, 1.06 | |
3 | 288,497 | 2,615 | 912 | 1.09 | 1.04, 1.14 | |
4 | 266,254 | 3,122 | 1,220 | 1.47 | 1.40, 1.53 | |
Moderate physical activity, hours/weekf | <0.01 | |||||
≥7 | 466,369 | 3,445 | 741 | 1.00 | Referent | |
4–7 | 485,946 | 3,839 | 822 | 1.11 | 1.06, 1.16 | |
1–3 | 455,798 | 3,869 | 905 | 1.18 | 1.13, 1.24 | |
<1 | 180,796 | 1,727 | 1,042 | 1.30 | 1.22, 1.37 | |
Inactive | 213,540 | 2,683 | 1,327 | 1.54 | 1.46, 1.62 | |
Vigorous physical activity, times/weekf | <0.01 | |||||
≥5 | 384,706 | 2,852 | 746 | 1.00 | Referent | |
3–4 | 525,965 | 4,005 | 775 | 1.04 | 0.99, 1.09 | |
1–2 | 403,721 | 3,413 | 907 | 1.15 | 1.09, 1.21 | |
<1 | 237,415 | 2,135 | 997 | 1.21 | 1.14, 1.28 | |
Inactive | 250,641 | 3,158 | 1,323 | 1.55 | 1.47, 1.63 |
Age-standardized mortality rate per 100,000 person-years, standardized to the age distribution of the cohort in men and women.
Adjusted for age, race/ethnicity, education, smoking status, physical activity, and alcohol consumption.
Weight (kg)/height (m)2.
Adjusted for moderate physical activity.
Group 1: men <94 cm, women <80 cm; group 2: men 94–<102 cm, women 80–<88 cm; group 3: men 102–<110 cm, women 88–<96 cm; group 4: men ≥110 cm, women ≥96 cm.
Adjusted for body mass index.