Table 1.

Numbers of Cases and Controls and Percentages of Smokers and Drinkers^a

	Never and Current Cigarette-Only Smokers						Never and Ever Consumers of Alcohol
Study Location (Reference No.)	No.				%		No.				%
	Larynx	Pharynx	Oral Cavity	Controls	Neverb	≥10 Cigarettes/Dayc	Larynx	Pharynx	Oral Cavity	Controls	Neverd	≤5 Drinks/Daye	≤10 Drinks/Daye
Total	1,761	2,453	1,990	10,114	59.6	83.1	2,551	3,693	3,116	15,589	27.0	79.8	93.7
Europe
Milan, Italy (41)	184	51	41	1,194	48.0	82.9	237	61	43	1,484	20.0	74.6	98.7
Aviano, Italy (42)	104	174	65	579	47.8	81.5	145	215	83	844	6.8	45.4	80.4
Italy (43)	286	290	92	1,632	58.8	74.0	430	393	120	2,483	9.8	79.0	96.8
Switzerland (44)	101	201	121	683	60.9	93.6	123	231	132	846	50.1	93.1	98.6
Central Europe (45)	272	80	115	557	49.4	85.1	372	146	183	850	7.3	86.4	97.6
North America
New York City, NY (10)	0	303	335	458	53.7	93.4	0	435	468	793	30.9	80.8	90.1
Seattle, WA (46)	0	115	132	309	62.1	88.9	0	163	210	598	7.5	94.4	98.0
Iowa (47)	55	96	157	431	65.4	92.6	91	160	252	751	44.3	88.0	96.9
Tampa, FL (48)	46	37	19	516	66.7	93.0	61	56	22	879	39.8	96.2	98.9
Los Angeles, CA (49)	58	87	35	605	76.4	67.8	86	167	52	1,004	24.9	92.4	97.5
Houston, TX (49)	88	227	156	500	75.4	85.4	153	424	234	862	45.8	96.4	99.6
Boston, MA (11)	57	131	80	280	69.6	87.1	111	291	137	659	10.5	88.3	95.4
South/Central America
Puerto Rico (50)	0	116	51	273	71.8	87.0	0	192	87	487	22.8	67.6	87.5
Latin America (22)	510	340	278	986	48.8	82.0	742	440	363	1,517	32.0	64.7	77.3
International (51)	0	205	313	1,111	67.3	80.7	0	319	730	1,532	55.4	82.3	94.9

^aData are from the International Head and Neck Cancer Epidemiology (INHANCE) Consortium of case-control studies of head and neck cancer.

^bPercentage of never and current cigarette-only smoking control subjects (n = 10,114).

^cPercentage of current cigarette-only smoking control subjects (n = 4,091).

^dPercentage of never and ever drinking control subjects (n = 15,589).

^ePercentage of drinking control subjects (n = 11,375).