Appendix Table 1.
Simulated Bias, Robust Standard Error, and Confidence Limit Coverage for Standard Marginal Structural and Marginal Structural Measurement-Error Cox Models Under an Alternative and Null Hypothesis and Nondifferential and Independent Misclassification of Treatment, 10,000 Samples of Size 1,000
| Marginal Structural Cox Model | Bias (MCSE) | SE (MCSE) | CL Coverage % (MCSE)a |
| Alternative hypothesis | |||
| Standard | −0.162 (0.002) | 0.213 (0.001) | 88.4 (0.3) |
| Measurement error | −0.003 (0.003) | 0.296 (0.001) | 95.2 (0.2) |
| Null hypothesis | |||
| Standard | 0.001 (0.002) | 0.215 (0.001) | 4.6 (0.2) |
| Measurement error | −0.001 (0.003) | 0.292 (0.001) | 5.4 (0.2) |
Abbreviations: CL, confidence limits; MCSE, Monte Carlo simulation error; SE, standard error.
a
Type 1 error rate under null hypothesis.