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. 2009 Dec 2;171(1):14–23. doi: 10.1093/aje/kwp377

Table 3.

Hazard Rate Ratios for Incident Coronary Heart Disease From Cox Regression Models, by Race, Atherosclerosis Risk in Communities Study, 1987–2004

dbSNPa ID No. African Americans
 Whites
Model 1b
 Model 2c
 Model 1b
 Model 2c
HRR 95% CI P Valued HRR 95% CI P Valued HRR 95% CI P Valued HRR 95% CI P Valued
rs599839 1.06 0.91, 1.24 0.425 1.07 0.91, 1.25 0.397 1.10 1.00, 1.21 0.044 1.02 0.93, 1.12 0.684
rs17465637 1.02 0.87, 1.19 0.845 1.01 0.85, 1.19 0.942 1.04 0.95, 1.13 0.421 1.04 0.95, 1.13 0.439
rs17672135 0.90 0.72, 1.14 0.395 0.89 0.70, 1.14 0.361 1.06 0.94, 1.19 0.333 1.05 0.93, 1.19 0.405
rs2943634 0.98 0.85, 1.13 0.797 1.00 0.86, 1.15 0.954 1.05 0.97, 1.14 0.243 1.02 0.94, 1.11 0.553
rs383830 1.11 0.96, 1.28 0.166 1.06 0.91, 1.23 0.431 1.05 0.95, 1.15 0.344 1.03 0.94, 1.14 0.493
rs6922269 1.04 0.90, 1.19 0.587 1.05 0.90, 1.21 0.537 1.03 0.95, 1.12 0.487 1.01 0.93, 1.11 0.734
rs1333049 0.93 0.79, 1.11 0.426 0.92 0.77, 1.10 0.372 1.14 1.06, 1.24 <0.001 1.17 1.08, 1.26 <0.001
rs501120 1.07 0.92, 1.24 0.380 1.08 0.92, 1.25 0.342 1.14 1.01, 1.28 0.030 1.18 1.05, 1.33 0.006
rs17228212 0.96 0.78, 1.20 0.746 0.96 0.77, 1.19 0.723 1.05 0.96, 1.14 0.283 1.03 0.94, 1.12 0.512
rs8055236 1.00 0.87, 1.15 0.992 1.02 0.88, 1.18 0.790 0.92 0.84, 1.01 0.096 0.94 0.85, 1.03 0.201
rs7250581 1.60 0.99, 2.59 0.054 1.39 0.84, 2.31 0.204 1.07 0.97, 1.19 0.167 1.05 0.95, 1.16 0.361
rs688034 0.99 0.78, 1.25 0.921 0.98 0.78, 1.25 0.904 0.96 0.89, 1.04 0.351 0.94 0.86, 1.02 0.131

Abbreviations: CI, confidence interval; HRR, hazard rate ratio; ID, identification; rs, reference SNP; SNP, single nucleotide polymorphism.

a

The National Center for Biotechnology Information's SNP database (http://www.ncbi.nlm.nih.gov/SNP/).

b

Results were adjusted for age and gender.

c

Results were adjusted for age, gender, body mass index, smoking, diabetes case status, hypertension case status, high density lipoprotein cholesterol, and low density lipoprotein cholesterol.

d

Analysis was performed using an additive genetic model, coded with respect to the risk allele identified by the Wellcome Trust Case Control Consortium (2).