Table 3.
dbSNPa ID No. | African Americans |
Whites |
||||||||||
Model 1b |
Model 2c |
Model 1b |
Model 2c |
|||||||||
HRR | 95% CI | P Valued | HRR | 95% CI | P Valued | HRR | 95% CI | P Valued | HRR | 95% CI | P Valued | |
rs599839 | 1.06 | 0.91, 1.24 | 0.425 | 1.07 | 0.91, 1.25 | 0.397 | 1.10 | 1.00, 1.21 | 0.044 | 1.02 | 0.93, 1.12 | 0.684 |
rs17465637 | 1.02 | 0.87, 1.19 | 0.845 | 1.01 | 0.85, 1.19 | 0.942 | 1.04 | 0.95, 1.13 | 0.421 | 1.04 | 0.95, 1.13 | 0.439 |
rs17672135 | 0.90 | 0.72, 1.14 | 0.395 | 0.89 | 0.70, 1.14 | 0.361 | 1.06 | 0.94, 1.19 | 0.333 | 1.05 | 0.93, 1.19 | 0.405 |
rs2943634 | 0.98 | 0.85, 1.13 | 0.797 | 1.00 | 0.86, 1.15 | 0.954 | 1.05 | 0.97, 1.14 | 0.243 | 1.02 | 0.94, 1.11 | 0.553 |
rs383830 | 1.11 | 0.96, 1.28 | 0.166 | 1.06 | 0.91, 1.23 | 0.431 | 1.05 | 0.95, 1.15 | 0.344 | 1.03 | 0.94, 1.14 | 0.493 |
rs6922269 | 1.04 | 0.90, 1.19 | 0.587 | 1.05 | 0.90, 1.21 | 0.537 | 1.03 | 0.95, 1.12 | 0.487 | 1.01 | 0.93, 1.11 | 0.734 |
rs1333049 | 0.93 | 0.79, 1.11 | 0.426 | 0.92 | 0.77, 1.10 | 0.372 | 1.14 | 1.06, 1.24 | <0.001 | 1.17 | 1.08, 1.26 | <0.001 |
rs501120 | 1.07 | 0.92, 1.24 | 0.380 | 1.08 | 0.92, 1.25 | 0.342 | 1.14 | 1.01, 1.28 | 0.030 | 1.18 | 1.05, 1.33 | 0.006 |
rs17228212 | 0.96 | 0.78, 1.20 | 0.746 | 0.96 | 0.77, 1.19 | 0.723 | 1.05 | 0.96, 1.14 | 0.283 | 1.03 | 0.94, 1.12 | 0.512 |
rs8055236 | 1.00 | 0.87, 1.15 | 0.992 | 1.02 | 0.88, 1.18 | 0.790 | 0.92 | 0.84, 1.01 | 0.096 | 0.94 | 0.85, 1.03 | 0.201 |
rs7250581 | 1.60 | 0.99, 2.59 | 0.054 | 1.39 | 0.84, 2.31 | 0.204 | 1.07 | 0.97, 1.19 | 0.167 | 1.05 | 0.95, 1.16 | 0.361 |
rs688034 | 0.99 | 0.78, 1.25 | 0.921 | 0.98 | 0.78, 1.25 | 0.904 | 0.96 | 0.89, 1.04 | 0.351 | 0.94 | 0.86, 1.02 | 0.131 |
Abbreviations: CI, confidence interval; HRR, hazard rate ratio; ID, identification; rs, reference SNP; SNP, single nucleotide polymorphism.
The National Center for Biotechnology Information's SNP database (http://www.ncbi.nlm.nih.gov/SNP/).
Results were adjusted for age and gender.
Results were adjusted for age, gender, body mass index, smoking, diabetes case status, hypertension case status, high density lipoprotein cholesterol, and low density lipoprotein cholesterol.
Analysis was performed using an additive genetic model, coded with respect to the risk allele identified by the Wellcome Trust Case Control Consortium (2).