Table 1.

Gene modules identified by KMF

Module	Function
1	Lipid metabolism and lipid processing.
2	Signaling proteins, intracellular and membrane protein-mediated: GPCR signaling, chemokine/TNF-α receptor signaling and ion channel-related signaling.
3	Glucose metabolism: glycolysis and pentose phosphate pathway.
4	Post-translational modification: ubiquitin-proteasome pathway, protein folding, transportation, phosphorylation.
5	Reactive oxygen species (ROS) homeostasis, redox system regulation and the TCA cycle.
6	Energy: ATP and GTP metabolism.
7	Protein synthesis: translation initiation and transcription.
8	Amino acid metabolism and urea cycle.
9	Apoptosis: executors and regulators.