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DA induces cAMP formation in ovarian follicles only in the presence of the oocyte, and the effect is blocked by a β-adrenoreceptor antagonist. Stripped columns, antral follicles without oocytes; dark columns, follicles containing oocytes; CO, control; DA, DA at 10 μM; DA/Prop, DA at 10 μm and propranolol at 50 μM. The number of independent observations per group is indicated above each bar. ∗, P < 0.05 vs. control and DA/Prop-treated groups.
