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. Author manuscript; available in PMC: 2009 Dec 31.
Published in final edited form as: J Immunol. 2009 Mar 1;182(5):2665–2671. doi: 10.4049/jimmunol.0802221

Figure 5.

Figure 5

Blockade of TGFβ exacerbated EAE in IL-17RA −/− mice. Wild type mice (WT), IL-17RA +/− (Het), and IL-17RA −/− littermates were immunized with MOG35–55 peptide to elicit EAE. Anti-TGFβ antibodies were administered at day 5 and day 9. Clinical signs and scores were recorded as described in Materials and Methods. Data were the average clinical scores from mice that have shown clinical signs of EAE. Each point represents the mean of 5–8 animals and vertical lines are s.e.m. Where no error bar appears, the s.e.m = 0. * p < 0.05 compared to the IL-17RA−/− group. Statistical analysis was performed using one-way analysis of variance test (ANOVA) followed by Tukey’s post hoc t-test.