Table 1.
Penetrance Tables for 2-way interactions. Penetrance tables of nine different models with 2-way interactions. SNP1 has three genotypes AA, Aa, aa and SNP2 has three different genotypes BB, Bb, bb. Each cell of a penetrance table represents the probability of being affected given the cell genotype.
| Model 1 | Model 2 | Model 3 | |||||||||
| bb | Bb | BB | bb | Bb | BB | bb | Bb | BB | |||
| aa | 0 | 0 | 0 | aa | 0 | 0 | .4 | aa | 0 | 0 | .5 |
| Aa | 0 | 0 | .6 | Aa | 0 | 0 | .4 | Aa | 0 | 0 | .5 |
| AA | 0 | .6 | .6 | AA | .4 | .4 | 0 | AA | .5 | .5 | 1 |
| Model 4 | Model 5 | Model 6 | |||||||||
| bb | Bb | BB | bb | Bb | BB | bb | Bb | BB | |||
| aa | .1 | .1 | .2 | aa | .1 | .1 | .2 | aa | .1 | .1 | .2 |
| Aa | .1 | .1 | .2 | Aa | .1 | .1 | .2 | Aa | .1 | .1 | .2 |
| AA | .2 | .2 | .36 | AA | .2 | .2 | .8 | AA | .2 | .2 | .1 |
| Model 7 | Model 8 | Model 9 | |||||||||
| bb | Bb | BB | bb | Bb | BB | bb | Bb | BB | |||
| aa | .12 | .12 | .27 | aa | .12 | .27 | .12 | aa | .36 | .36 | .36 |
| Aa | .12 | .12 | .27 | Aa | .27 | .12 | .27 | Aa | .36 | .60 | .60 |
| AA | .27 | .27 | .12 | AA | .12 | .27 | .12 | AA | .36 | .60 | .36 |