Figure 1.
Chloride and urea transport across the oocyte membrane after expression of the erythroid urea transporter hUT-B1 or red blood cells anion exchangers (tAE1, trout exchanger; mAE1, mouse exchanger). (A) Chloride exchange and urea transport of mAE1, tAE1, and hUT-B1 expressed in oocytes (compare with water-injected control). The flux was calculated from initial rates of uptake (5 min 14C-urea uptake; 15 min 36Cl uptake) after 5 days postinjection (incubation at 18°C). (Bars = mean ± SE; number of oocytes, n = 8.) (B) Time course of urea uptake in oocyte expressing tAE1 and hUT-B1 (compare with water-injected control). (n = 8.)