Predictive |
Available before irradiation that predicts a subsequent increased risk for organ specific radiation toxicity. |
ATM mutant homozygosity [14], circulating IL-1 and IL-6 may be in this class for pulmonary toxicity [15]. Chromosomal aberrations and micronuclei might be in this category for oncogenic risk |
Prognostic |
Available at any time after the exposure that predicts a subsequent increased risk for a more severe disease course. |
TGFβ1 levels may be in this class for pulmonary toxicity [10, 16], FGF2 may also be in this class for fibrovascular complications [16]. |
Diagnostic |
Available at the time of symptom presentation and which implicate radiation as the specific cause. |
None. |
Dosimetric |
Available at some point after exposure that can determine the dose delivered to one or more organs. |
Lymphocyte chromosomal aberrations for bone marrow exposure. |