Figure 4.

aV aptamer as a multiple state system. (a) The 2° of the aV aptamer. (b) The observed efficiency distribution of the aV aptamer at Mg²⁺ concentration of 2 mM, before blink-filtering. (c) The blink-filtered efficiency distribution of the aV aptamer. (d) The denoised distribution corresponding to b. (e) The observed efficiency distribution, before blink-filtering, resulting from the addition of 2 μM VEGF. (f) The blink-filtered efficiency distribution corresponding to e. (g) The denoised distribution corresponding to d.