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(a) Ribbon drawing of hRXRα/hPPARγ LBD heterodimer (PDB 3E00, also see Figure 2). (b) The detail view of the equivalent amino acid sidechains of mouse RXRα K422 and mouse PPARγ E405. The shortest distance between the negative (side chain carboxyl group of E405) and positive (side chain amino group of K422) charges is also displayed.
