Table 2.
Costs (in 2008 USD) included in decision tree.
| Variable | Baseline estimate | Range for sensitivity analysis | Source or references |
|---|---|---|---|
| Cost of GBS rectal-vaginal culture | |||
| $50 | $30–$75 | [8, 18, 32, 34, 41] | |
| Cost of GBS rectal-vaginal culture with susceptibility testing | [34] | ||
| $59 | $35–$89 | [36] | |
| Cost of maternal antibiotic therapy | |||
| One dose of 5 million units of penicillin G | |||
| $18 | $9–$27 | ||
| Second dose of 2.5 million units of penicillin G | |||
| $11 | $6–$17 | ||
| One dose of 2 grams of cefazolin | |||
| $14 | $7–$21 | ||
| One dose of 900 milligrams of clindamycin | |||
| $18 | $9–$27 | ||
| One dose of 500 milligrams of erythromycin | |||
| $16 | $8–$24 | ||
| One dose of 1 gram of vancomycin | |||
| $12 | $6–$18 | ||
| Cost of neonatal CBC | [22, 34, 38, 39] | ||
| $15 | $8–$41 | ||
| Cost of neonatal blood culture | [22, 34, 40] | ||
| $20 | $10–$26 | ||
| Cost of maternal anaphylaxis case | |||
| $11 160 | $1186–$30 286 | [8, 33, 38, 39] | |
| Cost of maternal death due to anaphylaxis | |||
| $1 211 432 | $1 090 288–$1 332 575 | [8] | |
| Direct cost of early onset GBS sepsis case term infant | |||
| $19 774 | $17 723–$21 824 | [38, 39, 41] | |
| Total (direct and indirect) cost of early onset GBS sepsis case term infant | |||
| $81 599 | $67 764–$95 433 | [38, 39, 42] | |
GBS: group B streptococci; CBC: complete blood count.