Table 4.
Pearson's correlation coefficients between formula-predicted pulmonary hypertension using 25 mmHg cut off point and putative predictors of pulmonary hypertension in the studied 37 patients with IPF
| Characteristics | r | P value |
|---|---|---|
| Radiological predictors | ||
| Hilar width | 0.357* | 0.03* |
| Hilar/thoracic index ≥ 35 | 0.473** | 0.003** |
| RDPA width on CXR | 0.232 | 0.167 |
| LDPA width on CXR | 0.247 | 0.140 |
| Cardiothoracic ratio | 0.019 | 0.912 |
| MPAD on CT | 0.104 | 0.541 |
| MPAD > 29 | 0.229 | 0.173 |
| MPAD/AD > 1 | 0.229 | 0.173 |
| A/B >1 | 0.186 | 0.270 |
| Pulmonary function tests | ||
| FEV1, L | −0.293 | 0.078 |
| FEV1, % predicted | −0.276 | 0.098 |
| FVC, L | −0.066 | 0.697 |
| FVC, % predicted | 0.068 | 0.688 |
| FEV1/FVC | −0.469** | 0.003** |
| FVC% pred/DLCO% pred | 0.329* | 0.047** |
| TLC, L | −0.085 | 0.616 |
| TLC, % predicted | −0.072 | 0.673 |
| DLCO, mL/mm Hg/min | −0.253 | 0.13 |
| DLCO, % predicted | −0.259 | 0.121 |
| Room air resting arterial blood gases | ||
| O2 saturation | −0.952** | 0.000** |
| O2 tension | −0.712** | 0.000** |
| CO2 tension | 0.127 | 0.453 |
| Echo measured RVSP, mm Hg | 0.600** | 0.000** |
PH = pulmonary hypertension, FEV1 = forced expiratory volume in first second, FVC = forced vital capacity, TLC = total lung capacity, DLCO = diffusing capacity of the lung for carbon monoxide, RVSP = right ventricular systolic pressure as measured by trans thoracic echocardiography, RDPA = right descending pulmonary artery, LDPA = left descending pulmonary artery, MPAD = main pulmonary artery diameter, AD = aortic diameter, A/B = arterial/accompanying bronchus diameter;
Correlation is significant at the 0.05 level (two-tailed);
Correlation is significant at the 0.01 level (two-tailed)