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. Author manuscript; available in PMC: 2010 Jan 4.
Published in final edited form as: J Org Chem. 2008 Aug 8;73(18):7219–7223. doi: 10.1021/jo801152c

Table 3.

Microfluidic Synthesis of 3-(1,2,4-Oxadiazol-5-yl)propanoic Acids from Arylnitriles and Succinic Anhydride

entry ArCN product yielda (%)
1 graphic file with name nihms159101t28.jpg graphic file with name nihms159101t29.jpg
18 		46
2 graphic file with name nihms159101t30.jpg graphic file with name nihms159101t31.jpg
19 		45
3 graphic file with name nihms159101t32.jpg graphic file with name nihms159101t33.jpg
20 		62
a

Isolated yield of pure product after purification of crude reaction mixture using preparative HPLC.