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Total serum IgG, IgG1 and IgG2a levels of non-vaccinated control and RB51-vaccinated rats 3 weeks after challenge with B. abortus biotype 1 (A) and at necropsy (B). Antibody titers are reported as mean ± SE. Statistically significant difference among RB51-vaccinated, non-vaccinated pregnant and non-pregnant control rats are indicated by asterisks (*p < 0.05 and †p < 0.001).
