Table 4.
Relative D10 value (mean ± SD) of cells treated with 15 μM NaAsO2 with and without 1 mM NAC.
Cell | With 1 mM NAC | Without 1 mM NAC |
---|---|---|
Wild-type | 53.37 ± 2.54 | 68.19 ± 1.64* |
ATM−/− | 1.81 ± 0.52 | 4.84 ± 0.79* |
XRCC3−/− | 9.21 ± 1.79 | 31.29 ± 2.09* |
RAD54−/− | 10.12 ± 2.19 | 40.37 ± 0.85* |
KU70−/− | 50.58 ± 0.56 | 61.27 ± 1.01* |
RAD54/KU70−/− | 19.09 ± 3.30 | 36.12 ± 7.05* |
UBC13−/− | 3.22 ± 0.50 | 6.49 ± 0.78* |
FANCC−/− | 21.78 ± 1.10 | 36.34 ± 4.39* |
REV3−/− | 17.26 ± 3.56 | 22.92 ± 0.89 |
XPA−/ | 16.55 ± 2.81 | 19.42 ± 0.39 |
XPG−/ | 16.15 ± 2.40 | 18.65 ± 0.74 |
POL-β−/− | 41.08 ± 3.59 | 54.52 ± 1.47* |
Abbreviations: FANCC, Fanconi anemia complementation group C; UBC13, ubiquitin-conjugating enzyme 13.
p < 0.05, compared with wild-type cells by one-way ANOVA.