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Water intake and urine volume in microsomal prostaglandin E synthase-1 (mPGES-1) wild-type (WT) and knockout (KO) mice following a 14-day treatment with vehicle (equivalent amount of saline, ip once a day) or LiCl (4 mmol·kg−1·day−1 ip once a day). A: urine volume. B: water intake. Values are means ± SE; n = 5–7/group. *P < 0.01 vs. WT/vehicle. #P < 0.01 vs. KO/LiCl.
