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. 2009 Sep 23;297(6):F1622–F1631. doi: 10.1152/ajprenal.00078.2009

Fig. 6.

Fig. 6.

Decreased mitogen-activated protein kinase phosphatase 5 (MKP5) mRNA expression in glomeruli and mesangial cells of OD mice. Glomeruli were microdissected from OD and O mice (n = 10/group). MKP5 mRNA expression was determined by a real-time PCR. A: glomeruli. **P < 0.01 vs. glomeruli of O mice. B: mesangial cells were isolated from 2 separate mice of Y, YD, O, and OD, respectively. *P < 0.05 vs. mesangial cells from young controls (n = 2 cell lines/age). ##P < 0.01 vs. mesangial cells from old controls (n = 2 cell lines/group).