Fig. 2.
Mechanical strain induces proliferation in urothelium of the ureter. A: cross sections of the ureter from creksp;R26R-EYFP mice that express enhanced yellow fluorescent protein (EYFP; green) in uroepithelial cells were obtained 3 days after UUO. Increased expression of Ki-67 (red) is detected in uroepithelial cells of the ureter above the obstruction (UA; a), but not below the obstruction (UB; b). Scale bars = 50 μM. B: quantification of Ki-67 expression in uroepithelial cells above (UA) and below (UB) the obstruction. Values are means ± SE; n = 3.