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In situ hybridization of Four jointed 1 (Fjx1). Fjx1 is expressed in renal vesicles (rv), comma-shaped (c), and S-shaped (s) bodies in the developing nephrons in embryonic day 14.5 (E14.5) kidneys. Fjx1 expression is downregulated to undetectable levels in the adult kidneys, including the kidneys of mice with sham operation, UUO, and RUUO. Scale bars = 100 μm (top) and 10 μm (bottom).
