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. Author manuscript; available in PMC: 2010 Jan 4.
Published in final edited form as: J Neurochem. 2008 Dec 11;108(4):1009–1018. doi: 10.1111/j.1471-4159.2008.05839.x

Fig. 3.

Fig. 3

SOD1 mutants with high propensity to aggregate (A4V and G93A SOD1) do not interfere with aggregation of G85R SOD1. A. Immunoblot of P2 (upper panel) and S1 (lower panel) fractions of singly and doubly transfected HEK293FT cells. UT: untransfected cells. WT and mutant SOD1 notations are the same as in Fig 1. B. Quantification of the relative aggregation potentials of the G85R SOD1 when expressed alone and with other SOD1 constructs. Bars represent mean ± SEM (n = 4–8). Statistical analysis compares the aggregation of WT hSOD1 to G85R or G85R co-transfected with another construct *p < 0.05, #p < 0.005. Only G85R + WT was significantly different from G85R alone *p < 0.05; n.s. indicates non-significant differences.