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. 2009 Dec 24;2009:780874. doi: 10.1155/2009/780874

Figure 2.

Figure 2

c-MYC induced accumulation of ROS in HaCaT cells was partially reversed by AP-2α. (a) time course showed that as early as 9 hours after infection, ROS level was higher than control (*P < .05 versus control, n = 3); (b) AP-2 reduced the ROS induced by c-MYC. The intercellular ROS level was measured by DCF method 24 hours after infection. Overexpression of AP-2 alone did not increase ROS level while co-overexpression AP-2 with c-MYC significantly decreased the accumulation of ROS (*P < .05 versus Bg-II and AP-2; P < .05 versus MYC, n = 3).