Table 1.

Locally advanced rectal adenocarcinoma patients analysed by gene expression microarray.

Patient	Treatment1	Stage at Diagnosis2	Diagnostic biopsy grade & histology	Diagnostic biopsy cellularity3	Surgical biopsy grade & histology	Surgical biopsy cellularity3	Pathological stage4
CRT1	CRT	T2N1 M0	moderately differentiated adenocarcinoma	60%	poorly differentiated adenocarcinoma	60%	T3N2
CRT2	CRT	T3N1 M0	moderately differentiated adenocarcinoma	60%	moderately differentiated adenocarcinoma	60%	T3N1
CRT3	CRT	T3N0 M0	moderately differentiated adenocarcinoma	60%	moderately differentiated adenocarcinoma	50%	T3N0
CRT4	CRT	T4N1 M0	moderately differentiated adenocarcinoma	50%	moderately differentiated adenocarcinoma	50%	T2N0
RT1	RT	T2N0 M0	moderately differentiated adenocarcinoma	60%	moderately differentiated adenocarcinoma	60%	T3N0
RT2	RT	T2N1 M0	moderately differentiated adenocarcinoma	60%	moderately differentiated adenocarcinoma	60%	T2N1
RT3	RT	T2N0 M0	moderately differentiated adenocarcinoma	50%	moderately differentiated adenocarcinoma	60%	T3N2
RT4	RT	T2N0 M0	moderately differentiated adenocarcinoma	60%	moderately differentiated adenocarcinoma	60%	T3N0
CON1	None	T3N1 M0	moderately differentiated adenocarcinoma	75%	moderately differentiated adenocarcinoma	70%	T3N1
CON2	None	T2N1 M0	moderately differentiated adenocarcinoma	50%	moderately differentiated adenocarcinoma	50%	T3N1

¹ CRT = neoadjuvant concurrent chemoradiotherapy; RT = Short course pre-operative radiotherapy. ² MRI and clinical stage. ³ % Tumour versus normal cells in biopsy profiled. ⁴ Pathological stage post-preoperative therapy