Table 3.
Albumin to Creatinine Ratios (ACR) at Selected Time Points by Clinical Characteristics
| Patient/transplant characteristic | baseline ACR: median (range) | day 35 ACR: median (range) | day 100ACR: median (range) |
|---|---|---|---|
| Age <40 | 14 (2, 424) | 41 (5, 5644) | 29 (1, 1490) |
| Age ≥40 | 24 (2, 1346) | 80 (10, 16948) | 70 (9, 3367) |
| p=0.05 | p=0.11 | p=0.04 | |
| Female | 20 (2, 1346) | 92 (10, 2863) | 91 (7, 3367) |
| Male | 20 (2, 517) | 59 (5, 16948) | 45 (1,1490) |
| p=0.54 | p=0.32 | p=0.04 | |
| No TBI | 19 (2, 517) | 63 (7, 16948) | 59 (3, 3367) |
| TBI | 27 (3, 1346) | 98 (5, 2863) | 53 (1, 1490) |
| p=0.19 | p=0.31 | p=0.98 | |
| Autologous donor | 32 (8, 291) | 41 (13, 106) | 25 (9, 88) |
| Allogeneic (related) donor | 15 (2, 1346) | 59 (5, 5644) | 45 (1, 3367) |
| Allogeneic HLA-matched unrelated donor | 23 (2, 517) | 96 (8, 16948) | 90 (3, 1490) |
| p=0.12 | p=0.04 | p=0.006 | |
| No SOS* | 19 (2, 1346) | 60 (5, 16948) | 45 (1, 3367) |
| SOS | 40 (8, 319) | 231 (23, 5644) | 129 (21, 822) |
| p=0.02 | p=0.0006 | p=0.01 | |
| No hypertension | 20 (2, 517) | 52 (5, 5644) | 30 (1, 3367) |
| Hypertension | 22 (3, 1346)‡ | 121 (8, 16948)** | 100 (3, 1490) |
| p=0.67 | p=0.0001 | p=0.0005 |
‡
Defined as having an elevated BP measurement recorded between study enrollment and the start of conditioning regiment (day minus 7).
**
Defined as having an elevated BP measurement on at least two consecutive measurements taken between transplant and the timepoint specified in the respective column.
*
SOS: Sinusoidal obstruction syndrome