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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Neuropharmacology. 2009 Aug 19;57(7-8):694–701. doi: 10.1016/j.neuropharm.2009.08.002

Figure 1.

Figure 1

Identification of the T283M coding variant in an ADHD proband. Electropherograms from TCGE from control (upper panel) and subject (lower panel) (A). Chromatogram of dideoxynucleotide sequencing of T283M mutation using forward (upper panel) and reverse primers (lower panel) (B). Pedigree of the T283M proband (C). The black box indicates the proband carrying the T283M heterozygous variant and diagnosed with ADHD. Grey boxes represent family members carrying T283M but unaffected by ADHD. Schematic illustration of NET indicating the positions of T283M protein variant in TM5 (D). V245I, in TM4, is also represented.