Table 3.
Selectivity of inhibitor 38 against a panel of PTPs
 | ||||||||
|---|---|---|---|---|---|---|---|---|
| PtpA | PtpB | PTP1B | Tc-Ptp | VHR | CD45 | LAR | HCPtpA | |
| Ki (μM) | 1.4 ± 0.3 | >100 | >100 | >100 | >100 | >100 | >100 | 14.8 ± 1.9 |
| Selectivity | – | >70 | >70 | >70 | >70 | >70 | >70 | 11 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.