Table 3. Significance levels (p values) for (i) cervical precancer/cancer, (ii) progression to cervical precancer/cancer, and (iii) HPV persistence, among SNPs with p≤0.001 for an association with cervical precancer/cancer.
Gene | rs # | (i) CIN3/CA | (ii) CIN3/CA | (iii) HPV persistence |
vs. RC | vs. HPV persistence | Vs. RC | ||
DMC1 | RS5757133 | 0.0007 | 0.1590 | 0.1114 |
DUT | RS3784621 | 0.0004* | 0.1280 | 0.0262 |
GTF2H4 | RS2894054 | 0.0001* | 0.8742 | 0.0002 |
GTF2H4 | RS6926723 | 0.0004 | 0.6840 | 0.0034 |
IFNG | RS11177074 | 0.0003 | 0.0095 | 0.4011 |
OAS1 | RS12307655 | 0.0005* | 0.2790 | 0.0034 |
OAS2 | RS718802 | 0.0001 | 0.1844 | 0.0057 |
OAS3 | RS12302655 | 0.00008 | 0.1909 | 0.0025 |
POLN | RS17132382 | 0.0011 | 0.0103 | 0.5304 |
SULF1 | RS4737999 | 0.0001* | 0.8918 | 0.0020 |
SULF1 | RS4284050 | 0.0007 | 0.4994 | 0.0020 |
SULF1 | RS10108002 | 0.0010 | 0.5160 | 0.0181 |
TMC8,TMC6 | RS9893818 | 0.0003 | 0.0019 | 0.8434 |