Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Oct 2;87(1):69–77. doi: 10.1189/jlb.0509361

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 Society for Leukocyte Biology

PMC Copyright notice

Figure 6. — Decreased migration of PMNs through EGCG-treated collagen resistant to cleavage by MMP-8. Collagen gels were made resistant to cleavage by MMP-8 by treating them with EGCG. Migration of WT and MMP-8^−/− PMNs across EGCG-treated rat-tail collagen type 1 gels was compared with migration of WT and MMP-8^−/− PMNs across rat-tail collagen type 1 gels not treated with EGCG. PMNs on the 0.4-μm polycarbonate membrane (113 mm² surface area) were counted under a fluorescent microscope at 4 h and 24 h. Analysis of the data from three experiments (expressed as mean±sem) showed significantly decreased migration of WT PMNs across EGCG-treated collagen gels (open bars) when compared with their migration across collagen gels not treated with EGCG (solid bars), both at 4 h (*, P=0.01) and 24 h (#, P=0.01). No significant difference was noted in the MMP-8^−/− PMNs.