Table 2.
CRP SNP allele frequencies for African Americans from NHANES III and AASK participants
| CRP SNPs | Location | Alleles | Allele Frequencies |
P Valuea | |
|---|---|---|---|---|---|
| NHANES III (n = 450) | AASK (n = 642) | ||||
| rs2808630 | 3'-flanking region | A | 86% | 83% | 0.03b |
| G | 14% | 17% | |||
| rs1205 | 3'-flanking region | A | 21% | 18% | 0.03b |
| G | 79% | 82% | |||
| rs3093066 | 5'-flanking region | A | 24% | 22% | 0.3 |
| C | 76% | 78% | |||
| rs1417938 | Intron 1 | A | 87% | 88% | 0.3 |
| T | 13% | 12% | |||
| rs3093058 | 5'-flanking region | A | 84% | 81% | 0.08 |
| T | 16% | 19% | |||
| rs1800947c | Exon 2 | C | 1% | 1% | 0.6 |
| G | 99% | 99% | |||
a
Unadjusted for multiple comparisons.
b
Not statistically significance at an α = 0.008 level after applying a Bonferroni correction (α = n/6).
c
Data for rs1800947 are for all NHANES III African-Americans participants with DNA (n = 2108) because the data user agreement does not allow outputs with counts less than 5.