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Methylation in the CpG island encompassing the PTPRR isoform 1 start site in colorectal tumors.
| Tumor type1 | No. | Methylated (%)2 | Unmethylated (%) |
|---|---|---|---|
| Premalignant lesions | |||
| Polypoid | 28 | 23 (82) | 5 (18) |
| Nonpolypoid | 18 | 15 (83) | 3 (17) |
| Primary adenocarcinomas | 44 | 42 (95) | 2 (5) |
| Liver metastases3 | 8 | 8 (100) | 0 (0) |
1 The normal mucosa counterpart was also analyzed for 21 samples (see Results)
2 Positivity threshold: ≥ 5% alleles (see Methods)
3 Associated with 8 of the 44 primary cancers listed above
