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H2S exposure increases mRNA levels of HIF-1 target genes. Real-time reverse transcription-PCR was used to quantitate mRNA levels of HIF-1 target genes in wild-type or hif-1(ia04) worms exposed to H2S or hypoxia. The cDNA of nhr-57 (A) or K10H10.2 (B) is shown as the average increase ± SD relative to sir-2.1 cDNA levels, which do not change during H2S exposure.
