Table 1.
Highly Differentiated Loci on the X Chromosome
| Cluster Name | Positiona | Lengtha | Genesb | SNPsc | Percentd | Probability of Clustere |
|---|---|---|---|---|---|---|
| PDHA1 | 19.11–21.41 | 2.30 | 8 | 52 | 5.7 | 0.0139 |
| Centromere | 62.43–67.81 | 5.38 | 14 | 605 | 66.2 | <0.0001 |
| IL1RAPL2 | 104.41–104.64 | 0.23 | 1 | 36 | 3.9 | <0.0001 |
| TRPC5 | 109.56–111.08 | 1.52 | 9 | 79 | 8.6 | 0.0004 |
| AFF2 | 147.71–147.84 | 0.13 | 1 | 22 | 2.4 | 0.0020 |
a
Positions are expressed in Mb and are from HapMap Release 24 (NCBI build 36).
b
The number of Refseq genes in a given locus.
c
The number of high-FST SNPs within the boundaries of a given locus.
d
The number of high-FST SNPs in the cluster as a percentage of the total number of high-FST SNPs on the X chromosome (914).
e
The probability of observing as many or more high-FST SNPs under neutrality as determined by 104 coalescent simulations (see Material and Methods).